OMIM

Essential tremor may be the most common human movement disorder. The main feature of essential tremor is postural tremor of the arms, but the head, legs, trunk, voice, jaw, and facial muscles also may be involved. Aggravated by emotions, hunger, fatigue, and temperature extremes, the condition may cause a functional disability or even incapacitation. Autosomal dominant inheritance can be demonstrated in most families (summary by Higgins et al., 1997). Deng et al. (2007) provided a detailed review of the genetics of essential tremor. (190300)

MalaCards based summary

Tremor, Hereditary Essential, 1, also known as etm1, is related to essential tremor, and has symptoms including dysarthria, postural tremor and hand tremor. An important gene associated with Tremor, Hereditary Essential, 1 is DRD3 (Dopamine Receptor D3). The drugs Oxymetazoline and Phenylephrine have been mentioned in the context of this disorder. Affiliated tissues include testes, tongue and liver.

UniProtKB/Swiss-Prot

Tremor, hereditary essential 1: A common movement disorder mainly characterized by postural tremor of the arms. Head, legs, trunk, voice, jaw, and facial muscles also may be involved. The condition can be aggravated by emotions, hunger, fatigue and temperature extremes, and may cause a functional disability or even incapacitation. Inheritance is autosomal dominant.